MicroBooNE is a liquid argon time projection chamber (LArTPC) on the Booster Neutrino Beam at Fermi National Laboratory. Its primary goals are to conduct a νe appearance search to investigate the nature of the anomalous low-energy excess of electromagnetic events observed by MiniBooNE, study neutrino-argon interactions, and conduct research and development for future large-scale argon based detectors such as DUNE. A signiﬁcant background for MicroBooNE’s νe appearance measurement are photon showers from neutral pion decay, which can mimic the electromagnetic cascade signature of electrons from νe’s. Studying neutral pion production in the MicroBooNE detector provides the opportunity to better understand electromagnetic shower topologies in LArTPCs. Furthermore, conducting experimental neutrino-argon cross sections is crucial for constraining modeling systematics and calculating the neutrino energy and ﬂux accurately for future accelerator-based neutrino oscillation experiments. This thesis presents a measurement of νμ charged current single π0 diﬀerential production cross sections on argon in the MicroBooNE detector. This will be the ﬁrst of its kind on argon.