Biophysics

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Biophysics

The study of the physics of living systems (PoLS) brings the physicist’s style of inquiry to the phenomena of life. The tremendous range of phenomena encountered in living systems, which often have no analogs in the inanimate world, demands that the intellectual agenda of biological physics is exceptionally broad. Nevertheless, while celebrating this breadth, the first National Academies’ PoLS decadal survey identified four key conceptual questions to organize exploration of the field: What are the physics problems that organisms need to solve? How do living systems represent and process information? How do macroscopic functions of life emerge from interactions among many microscopic constituents? How do living systems navigate parameter space? Our faculty are address many aspects of these questions.

Biophysics Faculty and their Research Focus

  • Christopher Lynn

    Understanding how structure and function emerge in complex living systems, particularly the brain.

  • Benjamin Machta

    Statistical physics of biological systems; critical points and phase transitions, membrane systems.

  • Simon Mochrie

    Quantitative microscopy and image analysis. Chromatin organization and dynamics. Nuclear envelope physics. Phase transitions of soft matter.

  • Alison Sweeney

    Self-assembly and optical properties of molecular structures, biophysics, evolution of deep sea squid camouflage, combining theory with experiment.

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Graduate Program in Physical and Engineering Biology (PEB)

Yale’s Integrated Graduate Program in Physical and Engineering Biology (PEB) was established to train a new generation of scientists who are skilled at applying physical and engineering approaches to biological research, and who are also sufficiently sophisticated in their biological training that they can readily identify and tackle cutting-edge problems in the life sciences. The PEB leadership is committed to a new paradigm that transcends traditional, artificial, boundaries both between disciplines and also between research, teaching, and learning. 

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